Other
Part:BBa_K2592006:Design
Designed by: Janice Law Group: iGEM18_Hong_Kong_HKU (2018-09-23)
Strand 2 for in-vivo synthesis of Nano Drug Carrier-AS1411 (NDC-as)
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12INCOMPATIBLE WITH RFC[12]Illegal NheI site found at 13
Illegal NheI site found at 36 - 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal AgeI site found at 52
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
N.A.
Source
This part is modified from the design published in 'Genetic encoding of DNA nanostructures and their self-assembly in living bacteria. Elbaz et al. Nat Commun. 2016 Apr 19;7:11179.'. AS1411 aptamer sequence is from 'Antiproliferative Activity of G-rich Oligonucleotides Correlates with Protein Binding. Bates et al. The Journal of Biological Chemistry. 1999 Sep 10;274: 26369-26377.'.